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Dr. Huo

Qun "Treen" Huo, Ph.D.
Associate Professor
Graduate Program Coordinator
Joint Appointments in NanoScience Technology Center and Department of Chemistry (College of Science), with a Secondary Joint Appointment in Burnett School of Biomedical Science (College of Medicine) and Department of Mechanics, Materials and Aerospace Engineering (College of Engineering)
Phone: 407-882-2845
E-mail: Qun.Huo@ucf.edu
View Full Curriculum Vita

Education

  • Postdoctoral Fellowship – University of Miami, Miami, Florida
  • Ph.D. – University of Miami, Miami, Florida
  • M.Sc. – Sun Yatsen University, Guangzhou, P.R. China
  • B.Sc. – University of Science and Technology of China, Hefei, P.R. China

Research

  • Postdoctoral Fellowship – University of Miami, Miami, Florida
  • Ph.D. – University of Miami, Miami, Florida
  • M.Sc. – Sun Yatsen University, Guangzhou, P.R. China
  • B.Sc. – University of Science and Technology of China, Hefei, P.R. China

Positions

  • 2014-present – Graduate Program Coordinator, NSTC, University of Central Florida
  • 2005-present – Associate Professor, University of Central Florida
  • 2001-2005 – Assistant Professor, North Dakota State University

Research Summary

Our group specializes on the development and use of gold nanoparticles for biomedical and bioanalytical applications. We invented a nanoparticle-enabled dynamic light scattering assay (NanoDLSay) for chemical and biological detection and analysis (see below for an illustration). This technique detects the target analytes by monitoring gold nanoparticle size change upon specific binding with the target molecules and species using dynamic light scattering. This technique has so far been successfully applied for a wide range of analytes, including proteins, DNAs, viruses, toxic metal ions, and small chemicals with high to ultra-high sensitivity and excellent reproducibility. We are currently applying this technique for early cancer detection and research. We collaborate with researchers from UCF College of Medicine, MD Anderson Cancer Center Orlando, Florida Hospital Cancer Institute on various projects related to prostate cancer, breast cancer, lung cancer and pancreatic cancer detection and diagnosis.

Principle of NanoDLSay Technique

Research News Highlight

Dr. Huo’s recent article published in ACS Applied Materials and Interfaces on protein-gold nanoparticle interaction study is featured on the cover of the journal. Read the full article.

Current Funding

  • College of Science Seed Grant, 2014-2016, Clinical validation study of a new molecular test for aggressive prostate cancer screening

Previous Funding (within the last 5 years)

  • National Science Foundation CAREER award (PI) DMR 0239424 and 0552295: Gold nanoparticles with single surface functional groups: Synthesis and Study
  • National Science Foundation NIRT award (PI) DMI 0506531: NIRT: Total chemical synthesis, property and modeling studies of nanoparticle/polymer hybrid materials
  • Florida Department of Health, Bankhead-Coley Foundation 09BB-09 (PI): Development of a Homogeneous Immunoassay for Cancer Biomarker Detection
  • Florida Department of Health, Bankhead-Coley Foundation 09BC-02 (Co-PI): Development of a New Bioanalytical Instrument for Biomolecular Research and Diagnosis

Publications

Courses

  • Organic Chemistry I and II
  • Bioanalytical Technology (PSM Nanotechnology program)

Awards, Honors and Memberships

2008-presentNational Institute of Health (NIH) panel review member
2010Florida State University System, Scholar Boost Award
2010-presentAssociate Editor, Reviews in Nanoscience and Nanotechnology (RNN)
2008Natural Science Foundation of China Oversea Young Investigator award
2006-presentAssociate Editor, Colloids and Surfaces B: Biointerfaces (Elsevier)
2006US-Japan Young Researcher Exchange Program for Nanotechnology and Nanomanufacturing delegation team (sponsored by NSF and Japanese Ministry of Education, Culture, Sports, Science, and Technology)
2005National Science Foundation NIRT award (PI)
2003National Science Foundation CAREER award (PI)

Membership

  • Member, American Chemical Society
  • Member, American Association for Cancer Research
UCF NanoScience Technology Center | Research Pavilion 4th Floor | TEL: 407-882-1578 FAX: 407-882-2819 | 12424 Research Parkway Suite 400 Orlando, FL 32826 | nano@ucf.edu
Advanced Materials Processing and Analysis Center